Friday, June 12, 2009

What it was like...

First,let me show you something:


Now here's the scientific explanation from the article Scientists Find a Link Between Dopamine and Obesity :
The lower PET scan images, labeled FDG, show glucose metabolism in the brains of obese and control (comparison) subjects. There are no differences. The upper PET scans show where the radiotracer C-11 raclopride binds to dopamine receptors. These images show that obese subjects have fewer dopamine receptors than control subjects.

Brookhaven scientists have done extensive research showing that dopamine plays an important role in drug addiction. Among other things, they've found that addictive drugs increase the level of dopamine in the brain, and that addicts have fewer dopamine receptors than normal subjects.

"Since eating, like the use of addictive drugs, is a highly reinforcing behavior, inducing feelings of gratification and pleasure, we suspected that obese people might have abnormalities in brain dopamine activity as well," says psychiatrist Nora Volkow, who was also involved in the study.

Okay, so in plain language--bottom left PET scan shows the glucose metabolism of a "normie", the normal sized person who can pass by a Cinnabon shop or pizza place in the mall and never think about buying something unless he or she is hungry. And even then, they might forgo those heavenly smells in favor of something reasonable and healthy, let's say, a nice big salad. Yeah, they do that. That's why they're normies, and I'm not. It takes constant prayer and a lot of cell phone calls to other food addicts to get me past Lucifer Morningstar's playground, aka the food court. And I walk very fast.

The bottom right picture shows the glucose metabolism of an obese person, who is more than likely a food addict like me. The scientists say there's little difference in the glucose processing in the brains of the normie and the obese person. They look different to me, but they're the experts. Maybe it's just that everyone's brain looks different on a PET scan, or to coin an old phrase, "as individual as our fingerprints". Glucose, for those who might not recognize the word, is the word for the sugar that's in all of our bodies. There's little difference between the two, the scientists say. Huh. Maybe they should have scanned MY brain.

The top PET scans show where the party gets started. The normie (top left picture) has more open pleasure receptors, which are places in their brains where dopamine (the natural high stuff)is given a VIP pass to get in. Running, playing checkers, skipping rocks, smelling roses, hot-tubbing--all of these activities get into a normal person's "party-over-here" pleasure-seeking receivers.

No such luck with the obese person (top right picture). The bouncer squashes most of the dopamine's action at the front door. Stop right there, buddy. Unless the dopamine is carrying a bag filled with a triple cheeseburger with giant-sized chili cheese fries, an extra large mocha chocolate chip milk shake and a huge slab of Oreo-crust cheesecake, the Big "D" ain't gettin' past the velvet rope. The obese person's pleasure seeking brain, ONLY recognizes Dr. Feelgood when he has Ms. Nasty hanging on his arm looking like a syrupy-sweet concoction oozing with fat.

Angela's aside: No, I do not eat like that now. Not even close! [See note below.]In fact, at 400 lbs I couldn't eat all that. Not at one time, at least. I had to wait at least two hours before I could finish it. It would be gone by 10 pm, though.

This is only a small part of an obese food addiction process. There's so much more to it, and I don't have the energy to delve into all that right now. But I can imagine all those scientists and researchers at the U.S. Department of Energy's Brookhaven National Laboratory are trying to come up with the right combination of chemicals to make those dopamine receptors open up and be free. Good people, those scientists and researchers. It's just too bad that food addiction is so much more complex than brain chemistry. Some of those scientific types even think that anti-depressants could get those receptors working. Poor souls. They just don't know the power of the dark side.

More about this later. It's a very long story.

Note: On a daily basis, I eat carefully measured amounts of protein, vegetables and fruit. The only additions to this is one ounce of oatmeal in the morning, 64 or more ounces of water to drink throughout the day, and decaf coffee or tea after breakfast. No artificial sweeteners, either.

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